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Acyclovir triphosphate is a preferred substrate of viral DNA polymerase; it inhibits enzyme activity and, following its incorporation into viral DNA, induces strand breakage because it lacks the 3’-OH group of deoxyribose that is required for the attachment of additional nucleotides.
Regardless of the outcome of thrombolytic therapy or balloon dilation, a ?-blocker is administered to suppress imminent arrhythmias, unless it is contraindicated. Treatment of lifethreatening ventricular arrhythmias calls for an antiarrhythmic of the class of Na+-channel blockers, e. g. , lidocaine.

 

The immediate threat results not so much from the loss of erythrocytes, i. e. , oxygen carriers, as from the reduction in volume of circulating blood. To eliminate the threat of shock, replenishment of the circulation is essential. With moderate loss of blood, administration of a plasma volume expander may be sufficient. Blood plasma consists basically of water, electrolytes, and plasma proteins.
ACh stimulates receptors located on the subsynaptic membrane of the second neuron. Activation of these receptors causes the nonspecific cation channel to open. The resulting influx of Na+ leads to a membrane depolarization.

 

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